Every Woman Should Know Her Risk For Breast Cancer

Why are some women susceptible but not others?

Researchers at Rockefeller University have found that the body metabolizes estrogens into several different forms that can impact cancer development. One form, 2-hydroxyestrone (2-OHE1) tends to inhibit cancer growth. Another, 16-ά-OHE1) , actually encourages tumor development. A woman's "biochemical individuality" determines how much of each form is produced. Studies have shown that measuring the ratio of these two forms of estrogen provides an important indication of future risk for development if breast cancer. The studies also show that this risk can be modified!

What is the Estronex 2/16 Test?

The Estronex 2/16 Test is a measurement of these two important forms of estrogen: 2-OHE1 (the "good" estrogen and 16-ά-OHE1 (the "bad" estrogen is determines from a single urine specimen. Studies have shown that women with low Estronex 2/16 ratios have much higher rates of breast cancer. Low Estronex 2/16 rations also indicate increased long-term risk for other estrogen-sensitive cancers, including uterine, ovarian, cervical, and even head and neck cancers.

The following may contribute to your risk of developing estrogen-sensitive cancers:

Prolonged use of oral contraceptives
Synthetic hormone replacement therapy
Family history of breast cancer
Obesity or sedentary lifestyle
Consumption of 2 or more alcoholic drinks per day
Getting older
Never having children, or having your first after 35
Having breast high breast density
Being exposed to large amounts of radiation

What could be done to decrease a high ratio?

Consuming more foods containing indole-3-carbinole (I3C) can raise the Estronex 2/16 ration. I3C is found in cruciferous vegetables, like broccoli, cauliflower, cabbage, and Brussels sprouts. Nutritional supplements containing diindolylmethane (DIM), a more stable supplement closely related to I3C, have also been shown to raise the Estronex 2/16 ratio. Follow-up testing is strongly recommended to ensure that your treatment plan is effective over time.

What could be done to increase the ration?

Consume more ground flax seed or soy isoflavones, which favorably benefit the Estronex 2/16 ration.
Increase the amount of omega-3 oils from fish in your diet which have been shown to exert anti-cancer effects and improve the Estronex 2/16 ration.
Exercise and maintain a healthy weight.